Figure 6 | Scientific Reports

Figure 6

From: The enhanced atorvastatin hepatotoxicity in diabetic rats was partly attributed to the upregulated hepatic Cyp3a and SLCO1B1

Figure 6

The serum levels of ALT (a), AST (b), AKP (c), Alb (d), TBIL (e), DBIL (f), ROS (g) and the liver weight (h) in normal rats (CON), normal rats treated with 10 mg/kg atorvastatin (AL), 20 mg/kg atorvastatin (AM) and 40 mg/kg atorvastatin (AH); normal rats treated with only phenobarbital (PB), rats co-administrated with phenobarbital and 10 mg/kg atorvastatin (PB-AL), 20 mg/kg atorvastatin (PB-AM) and 40 mg/kg atorvastatin (PB-AH). Data are represented as means ± SD (n = 5) *p < 0.05, **p < 0.01 vs. CON, +p < 0.05, ++p < 0.01 vs. PB, #p < 0.05, ##p < 0.01 vs. AL, AM or AH.

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