Table 2 Marker expressions as predictor for BFFS, CFFS and PCDFS in PCa patients (n = 535), (univariate analysis; log rank test), significant p-values in bold (threshold p ≤ 0.05).

From: Estrogen receptors α and β and aromatase as independent predictors for prostate cancer outcome

 

Patients (n)

Patients (%)

BFFS

CFFS

PCDFS

Marker expression

5-year (%)

10-year (%)

p

5-year (%)

10-year (%)

p

5-year (%)

10-year (%)

p

ERα TS

Low

144

26.9

73

67

0.819

94

86

0.042

98

89

0.019

High

373

69.7

74

61

97

93

99

98

Missing

18

3.4

      

ERβ TS

Low

368

68.8

77

66

0.002

97

91

0.658

100

97

0.486

High

149

27.9

67

54

95

91

99

97

Missing

18

3.4

      

Aromatase TS

Low

131

24.5

66

54

0.016

94

90

0.225

98

91

0.668

High

386

72.1

77

65

97

91

99

98

Missing

18

3.4

      

Aromatase TE

Low

275

51.4

73

61

0.487

95

93

0.036

98

96

0.061

High

242

45.2

75

64

97

96

99

97

Missing

18

3.4

      
  1. Abbreviations: ERα = estrogen receptor alpha; ERβ = estrogen receptor beta; TE = tumor epithelial cells; TS = tumor stromal cells; BFFS = Biochemical failure free survival; CFFS = clinical failure free survival; PCDFS = prostate cancer death free survival.