Table 1 Bioassay of SSLOW samples in golden Syrian hamsters.

From: Reversible off and on switching of prion infectivity via removing and reinstalling prion sialylation

SSLOW inocula

ns/nt*

nPrPSc/nt** brain

nPrPSc/nt** spleen

Euthanized at days post-inoculation

103 fold diluted brain-derived

7/7

7/7

N/A

503, 503, 503, 503, 503, 591, 609

104 fold diluted brain-derived

7/7

7/7

N/A

504, 540, 551, 552, 556, 560, 577

PMCAb-derived

0/8

7/8

8/8

621

dsPMCAb-derived

0/6

0/6

0/6

614

rsPMCAb-derived

0/5

5/5

5/5

614

  1. *Number of animals with clinical signs (ns) over the total number of animals (nt) that survived to the end of the experiment.
  2. **Number of animals with PrPSc in brain homogenates or spleen homogenates (nPrPSc) over the total number of animals survived to the end of the experiment (nt).
Back to article page