Figure 4

Assessment of specificity and selectivity of the SPR biosensor.
(A) Detection of AFP on AuNP@anti-AFP1-coated chips, AuNP@anti-IgG-coated chips, and bare AuNP surface. The concentration of AFP was 100 ng/mL. (B) Cross-reaction of CEA, CYFRA 21-1, HSA, and IgG was detected using AuNP@anti-AFP1 conjugate-coated chips. The concentration of AFP was 100 ng/mL, and that of each of the other targets was 200 ng/mL.