Table 2 Comparison of SPR biosensor and electrochemiluminescence method for detection of AFP, CEA, and CYFRA 21-1.

From: A SPR biosensor based on signal amplification using antibody-QD conjugates for quantitative determination of multiple tumor markers

sample

Electrochemiluminescence

SPR biosensor

Relative error (%)

AFP

CEA

CYFRA21-1

AFP

CEA

CYFRA21-1

AFP

CEA

CYFRA21-1

1

8.6

5.2

6.8

7.8

5.5

6.3

9.3%

5.8%

7.3%

2

264

6.6

7.3

247

3.1

6.7

6.4%

9.0%

8.2%

3

774

23.4

6.7

813

21.2

6.2

5.0%

9.4%

7.5%

4

7.4

583

7.4

6.8

632

8.1

8.1%

8.4%

9.5%

5

4.8

126

6.4

3.4

137

5.8

8.3%

8.7%

9.4%

6

4.2

6.7

69.7

3.8

6.1

73.8

9.5%

8.9%

5.9%

7

12.1

9.2

257

10.9

10.1

274

9.9%

9.8%

6.6%

8

341

5.9

11.8

365

6.4

12.7

7.0%

8.5%

7.6%

9

15.7

37.5

458

14.3

41.2

499

8.9%

9.8%

9.0%

10

4.3

3.6

5.1

2.0

3.3

4.6

9.3%

8.3%

9.8%