Table 1 Clinical characteristics for all participants.

From: Deep sequencing reveals microbiota dysbiosis of tongue coat in patients with liver carcinoma

Clinical and pathological Indexes

Liver cancer patients

Healthy controls

P

  

N = 35

%

N = 25

%

 

Age (year)

50.30 ± 5.86

48.20 ± 6.03

0.19*

Gender

Female

5

14.3

5

20.0

0.728#

Male

30

85.7

20

80.0

BMI (kg/m2)

22.52 ± 1.55

22.56 ± 1.63

0.926

BCLC

0 (very early)

15

42.9

   

A (early)

20

57.1

   

AFP (ng/ml)

≤20

21

60.0

25

100

<0.001

>20

14

40.0

0

0

 

Tumor size (cm)

≦2

15

42.9

   

2< & ≦5

20

57.1

   

Tumor number

Single

34

97.1

   

Multiple

1

2.9

   

Tumor differentiation

I-II

26

74.3

   

III-IV

9

25.7

   

Liver cirrhosis

Yes

35

100

   

CTP score

A

35

100

   

HBsAg

Positive

35

100

   

Mild complication

No

35

100

   

ALT (U/L)

37.24 ± 22.61

19.36 ± 6.85

<0.001

AST (U/L)

34.51 ± 12.88

20.60 ± 4.95

<0.001

GGT (U/L)

53.00 ± 26.48

18.00 ± 9.29

<0.001

Total protein (g/L)

61.99 ± 5.72

75.12 ± 3.79

<0.001

Albumin (g/L)

34.18 ± 2.87

49.03 ± 2.17

<0.001

Globulin (g/L)

26.59 ± 3.23

26.10 ± 2.96

0.697

Total bilirubin (μmol/L)

17.69 ± 7.88

13.48 ± 4.89

0.023

Direct bilirubin (μmol/L)

7.51 ± 4.27

4.60 ± 1.73

<0.001

Indirect bilirubin (μmol/L)

10.10 ± 4.17

8.88 ± 3.48

0.240

Platelet (10E9/L)

128.97 ± 65.65

225.84 ± 63.98

<0.001

CA 199 (U/ml)

11.01 ± 7.62

8.09 ± 6.33

0.132

CA 125 (U/ml)

12.32 ± 6.75

9.10 ± 4.27

0.054

  1. The continuous variables were presented as mean ± SD.
  2. Abbreviations: BMI, body mass index; AFP, alphafetoprotein; HBsAg, hepatitis B surface antigen; ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, glutamyl transpeptidase; CTP score, Child-Turcotte-Pugh score; CA 199, carbohydrate antigen 19–9; CA 125, carbohydrate antigen 12–5.
  3. *Independent t-test.
  4. #Pearson Chi-Square test or Fisher exact test.
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