Figure 6
From: miR-224-3p inhibits autophagy in cervical cancer cells by targeting FIP200
miR-224-3p regulates autophagy through FIP200 down regulation.
(A,B) Levels of FIP200 and tubulin in C33A, SiHa and HeLa cells. Cells were transfected with miR-224-3p mimetic, NCm, miR-224-3p inhibitor or NCi (100 nM) for 24 h. Levels of FIP200 and tubulin were determined by Western blot. (C) The impact of miR-224-3p activation or inhibition on FIP200 mRNA levels were compared C33A, SiHa and HeLa cells. Data is represented as mean ± SD of n = 3 independent experiments. miR-224m = miR-224-3p mimetic; NCm = miRNA mimicsnegative control. *p < 0.05 as determined using student’s 2-tailed t-test.
