Figure 4 | Scientific Reports

Figure 4

From: Entinostat up-regulates the CAMP gene encoding LL-37 via activation of STAT3 and HIF-1α transcription factors

Figure 4

Induction of the CAMP gene is partly dependent on de novo protein synthesis.

De novo protein synthesis in HT-29 cells was inhibited by incubation with 1 μg/ml cycloheximide (CHX) in the presence or absence of 2.5 μM Entinostat for 24 h. The levels of the CAMP transcript were measured by qRT-PCR. CHX significantly reduced Entinostat-mediated induction of the CAMP gene *p < 0.05.

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