Figure 2 | Scientific Reports

Figure 2

From: A super gene expression system enhances the anti-glioma effects of adenovirus-mediated REIC/Dkk-3 gene therapy

Figure 2

Cytotoxicity after Ad-SGE-REIC treatment in glioma cell lines.

U87ΔEGFR (A,C) and GL261 (B,D) glioma cells were infected with Ad-SGE-REIC, Ad-CAG-REIC, or Ad-LacZ at an MOI of 10. Cell viability was examined 24, 48, and 72 h after infection. In cytotoxicity assays, the proliferation rate of malignant glioma cells was reduced in a time-dependent manner after treatment with Ad-SGE-REIC and the effect was stronger compared with that of Ad-CAG-REIC (*p < 0.05, **p < 0.01, ***p < 0.005, ****p < 0.001).

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