Figure 3 | Scientific Reports

Figure 3

From: Complement component 3 deficiency prolongs MHC-II disparate skin allograft survival by increasing the CD4+ CD25+ regulatory T cells population

Figure 3

C3 deficiency led to reduced inflammatory cytokine and chemotactic factor expression in allografts.

Bm12 mice were transplanted with tail skin grafts from Bm12 (Isografts), C3+/+ and C3−/− (allografts) mice. Grafts were harvested on day 10 after transplantation and expression of inflammatory cytokine and chemokine mRNA levels in grafts were measured by RT-qPCR (n = 5–6). One representative data set from three independent experiments is shown. *p < 0.05; **p < 0.01.

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