Table 3 Clinical and Laboratory Characteristics of Control and Syphilis Patients.

From: CXCL13, CXCL10 and CXCL8 as Potential Biomarkers for the Diagnosis of Neurosyphilis Patients

 

Control 1 (blood) (n = 63)

Control 2 (CSF) (n = 29)

Non-neurosyphilis (n = 123)

Neurosyphilis

Asymptomatic (n = 82)

Symptomatic (n = 109)

Male (%)

48 (68.5)

18 (62.1)

71 (57.7)

52 (63.4)

98 (89.9)

Age (Median, IQR)

44 (25–55)

46 (27–61)

52.5 (42.25–59.5)

52 (39–59)

53.5 (47–59)

1/Serum RPR titer (median, IQR)

0 (0–0)

0 (0–0)

32 (8–64)

64 (32–128)

63 (32–64)

CSF-WBC, cells/μl (median, IQR)

ND

1 (0–5)

1.1 (0–4.3)

8.8 (2.2–39.05)

9.9 (2–35.8)

CSF protein, g/l (Median, IQR)

ND

0.23 (0.1–0.4)

0.29 (0.23–0.34)

0.43 (0.29–0.57)

0.63 (0.46–0.89)

CSF VDRL (+) (%)

ND

0 (0)

0 (0)

67 (81.7)

109 (100)

CSF VDRL (−) and CSF-TPPA (+) (%)

ND

0 (0)

35 (28.2)

15 (18.3)

0 (0)

  1. Data are given as median (IQR), or frequencies.
  2. Abbreviations: RPR, Rapid Plasma Regain test; CSF, cerebrospinal fluid; VDRL, Venereal Research Laboratory; TPPA, Treponema pallidum particle agglutination assay; WBC, white blood cells; ND, not done.