Table 3 Differential mRNAs associated with muscle growth and development process by GO analysis.

From: Comparative transcriptome profiling of longissimus muscle tissues from Qianhua Mutton Merino and Small Tail Han sheep

Gene symbol

Description

QHMM (normalized counts)

STH (normalized counts)

Log2FoldChange

FDR

Style (STH vs.QHMM)

Enriched biological process

BCL9L

B-cell CLL/lymphoma 9-like protein

364.4

156.2

−1.2

5.16E-03

down

7

BTG1

Protein BTG1

670.5

3228.5

2.3

9.08E-05

up

4,10

CASQ1

Calsequestrin

45168.0

17353.3

−1.4

5.41E-04

down

1,8

CASQ2

Calsequestrin

620.4

248.1

−1.3

1.90E-02

down

8

CDH15

Cadherin-15

122.5

263.7

1.1

1.66E-03

up

5

CITED2

Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2

155.9

289.7

0.9

2.54E-02

up

7

CSRP3

cDNA, FLJ93801, Homo sapiens cysteine and glycine-rich protein 3 (cardiac LIMprotein) (CSRP3), mRNA

4896.3

18425.4

2.0

4.61E-02

up

1,9

FHOD3

FH1/FH2 domain-containing protein 3

502.7

172.0

−1.5

0

down

8,9

FOXP1

cDNA FLJ58267, highly similar to Forkhead box protein P1

233.3

382.1

0.7

2.45E-02

up

1,8

GPX1

Glutathione peroxidase

1529.1

761.9

−1.0

1.22E-06

down

3

HEYL

cDNA FLJ52278, highly similar to Homo sapiens hairy/enhancer-of-split related with YRPW motif-like (HEYL), mRNA

310.0

186.4

−0.7

7.27E-05

down

7

HLF

Hepatic leukemia factor

76.3

31.7

−1.3

1.02E-04

down

7

ITGA7

cDNA FLJ12486 fis, clone NT2RM2000566, highly similar to Integrin alpha-7

4307.8

1157.3

−1.9

0

down

1

KIAA1161

KIAA1161 ortholog

661.6

214.7

−1.6

1.19E-06

down

3

LMOD2

cDNA FLJ50049, highly similar to Mus musculus leiomodin 2 (cardiac) (Lmod2), mRNA

5623.4

12507.3

1.2

1.18E-08

up

9

MAFF

Transcription factor MafF

73.1

239.3

1.7

1.89E-03

up

7

MYF6

Myogenic factor 6

1688.6

4474.1

1.4

0

up

1,2,4,6,7,8,10

MYH6

myosin, heavy chain 6, cardiac muscle, alpha

12787.7

4502.7

−1.5

1.17E-10

down

8,9

MYL2

Myosin light chain 2

63933.5

23309.3

−1.5

7.13E-12

down

9

MYL6B

myosin, light chain 6B, alkali, smooth muscle and non-muscle

12018.3

1654.6

−2.9

3.77E-02

down

1

MYLK3

Myosin light chain kinase 3

265.8

94.1

−1.5

6.03E-06

down

8,9

MYOD1

Myoblast determination protein 1

232.5

37.5

−2.6

3.46E-06

down

1,2,3,4,6,7,8,10

MYOG

Myogenin

501.8

148.6

−1.8

2.41E-04

down

1,2,3,4,6,7,8,10

NEO1

Neogenin homolog 1 (Chicken), isoform CRA_a

390.1

178.1

−1.1

2.90E-06

down

5

OMYHCS

Myosin heavy chain slow

225230.0

88659.7

−1.3

3.66E-14

down

8,9

PPP3CB

Serine/threonine-protein phosphatase

1978.0

1122.0

−0.8

3.85E-02

down

3

RXRG

Retinoic acid receptor RXR-gamma

1104.1

273.7

−2.0

2.89E-06

down

1

SETD3

SET domain containing 3, isoform CRA_a

1297.1

719.0

−0.9

1.02E-04

down

5

STAC3

SH3 and cysteine rich domain 3, isoform CRA_a

5060.1

2569.4

−1.0

4.65E-03

down

3

XIRP1

xin actin-binding repeat containing 1

7518.7

37631.7

2.3

1.11E-06

up

8

  1. Enriched biological process: 1. skeletal muscle tissue development; 2. positive regulation of skeletal muscle fiber development; 3. skeletal muscle fiber development; 4. positive regulation of myoblast differentiation; 5. positive regulation of muscle cell differentiation; 6. muscle cell fate commitment; 7. muscle cell differentiation; 8. sarcomere organization; 9. myofibril assemly; 10. myoblast differentiation.