Figure 5: Self-organizing map (SOM) clustering and GO enrichment of DE genes.

(A) SOM clusters of DE genes showing their response patterns to the three treatment phases in WT and RNAi plants. The total number of DE data points in each cluster is indicated in parenthesis on top, and tissue representation (L, leaf; B, bark; X, xylem and R, root) listed at the bottom (see Methods). Solid and dashed lines represent the group mean of WT and RNAi plants, respectively. (B) GO enrichment analysis of six SOM clusters that showed different treatment response trajectories between genotypes. Hierarchical clustering of negative log10-transformed P values for GO enrichment was visualized in heatmaps according to the color scale. DE genes within each cluster are sorted by their tissue of origin in columns and color-coded, while GO terms are shown in rows.