Figure 6: Effect of TTd, monomeric, and fibrillar α-syn on the frequency of CD4+ T naive and memory subsets. | Scientific Reports

Figure 6: Effect of TTd, monomeric, and fibrillar α-syn on the frequency of CD4+ T naive and memory subsets.

From: Dopaminergic Receptors on CD4+ T Naive and Memory Lymphocytes Correlate with Motor Impairment in Patients with Parkinson’s Disease

Figure 6

Panel (a) Effects of TTd (left), monomeric (middle), and fibrillar α-syn (right) in cells from HS (open columns) and PD patients (hatched columns). Data are expressed as percentage variation with respect to control conditions (without TTd or α-syn), and are means ± SEM of n = 6–8 separate experiments each performed in duplicate. * = P < 0.05 and ** = P < 0.01 vs. control conditions, and # = P < 0.01 vs. HS. Panel (b) monomeric (hatched columns), and fibrillar α-syn (shaded columns) on DR expression in T naive (left), TCM (center) and TEM cells (right) from 5 HS. Data are means ± SEM. * = P < 0.05 and ** = P < 0.01 vs control (open columns); # = P < 0.01 vs monomeric α-syn.

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