Figure 6 | Scientific Reports

Figure 6

From: Helical unwinding and side-chain unlocking unravel the outward open conformation of the melibiose transporter

Figure 6

(A) The ribbon diagram highlights the helical torsion and orientation changes in helices TM2 and TM11 emphasizing the A56–G378–G379 knob. The bottom representation as QuickSurf in VMD depicts the exposure of the substrate binding site residues, where blue and red indicates basic and acidic residues, respectively. For the representation of the occluded state we have selected replica B.1. (B) Representation highlighting key residues in MelB substrate binding and transport.

Back to article page