Figure 8
From: Construction of a Corneal Stromal Equivalent with SMILE-Derived Lenticules and Fibrin Glue
Histological and TEM analysis of ALK in rabbits.
(A–C) H&E staining depicting the wound healing process of the graft after ALK. (g: graft; b: recipient bed). Bar: 20 μm. (F–G) TEM image depicting hemi-desmosomes (arrowheads) and newly synthesized basement membrane (arrows) at the epithelial-stromal interface. (I–K) TEM image demonstrating that keratocytes were activated at 0.5 and 2 months after ALK and reverted to the quiescent state at 3 months after ALK. (M–O) TEM image revealing that the collagen fibril spacing decreased and was arranged with a uniform spacing, similar to the normal cornea at 3 months after ALK. (D,H,L,P) Histological and TEM analysis of a normal rabbit cornea.
