Figure 5: Assessment of glomerular filtration rate: Excretion half-life (t1/2) of FITC-sinistrin in control (
) and water-restricted (
) SHR at baseline and at the end of the 4-week water restriction protocol.

Data are presented as mean ± SEM and were analyzed using repeated-measures ANOVA with Bonferroni’s post-hoc tests (2 comparisons). ***P ≤ 0.001 versus baseline. n = 8–10 per group.