Figure 6

Assessment of renal fibrosis: Bar graphs represent quantification of the (a) glomerular and (b) tubulointerstitial percentage area positively stained with picrosirius red in control () and water-restricted (
) SHR. Representative images of renal cortical fibrosis in (c) control and (d) water-restricted SHR at the end of the 4-week water protocol. Scale represents 100 μm. Data are presented as mean ± SEM. Data were analyzed using an unpaired t-test. #P ≤ 0.05 versus control SHR. n = 8–13 each.