Figure 7: Circulating renal immune cell infiltration and cytokine production: Circulating renal immune cell infiltration and cytokine production in control (
) and water-restricted (
) SHR at the end of the 4-week water restriction protocol.

(a) Circulating T cells (CD3+ cells), the proportion of (b) circulating T helper cells and cytotoxic T cells and (c) T cells producing IFN-γ, IL-4 and TNF-α, and (d) Th1:Th2 proportion of cytokine producing T cells (measured as the ratio of IFN-γ/IL-4). Data are presented as mean ± SEM. Data were analyzed using an unpaired t-test. ##P ≤ 0.01 versus control SHR. n = 7–13 each.