Figure 6
From: Porcine milk-derived exosomes promote proliferation of intestinal epithelial cells
Expression of proliferation-related genes and proteins in intestinal tissue.
(a–d) Expression of CDX2, PCNA, IGF-1R and p53 mRNAs, respectively. Expression of CDX2, PCNA and IGF-1R genes significantly increased at different treatment concentrations (0.125 μg and 0.25 μg treatment groups), except for the expression of IGF-1R in the 0.125 μg treatment group (P = 0.055). Meanwhile, p53 significantly decreased (n = 6). (e–h) Expression of CDX2, p53, IGF-1R and PCNA proteins, respectively. Except for the IGF-1R protein expression in the 0.25 μg treatment group which did not change significantly, expression levels of other proteins were consistent with those of their corresponding mRNAs (n = 6).
