Figure 1 | Scientific Reports

Figure 1

From: Computational understanding and experimental characterization of twice-as-smart quadruplex ligands as chemical sensors of bacterial nucleotide second messengers

Figure 1

Conformational pluralism of PyroTASQ.

(A). Conformational switch promoted by its interaction with quadruplexes: the formation of the intramolecular G-quartet triggers the fluorescence of the pyrene template. (B) Schematic representation of the possible ‘open’, ‘semi-closed’ (with one or two guanines stacking on the template, 1G and 2G, respectively) and ‘closed’ conformations of PyroTASQ.

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