Figure 1
From: High Fructose Diet inducing diabetes rapidly impacts olfactory epithelium and behavior in mice
EOG responses are decreased after 8 weeks of HFruD.
Global responses to octanol (a) or acetophenone (b) were recorded from olfactory mucosa of control (grey lines and white bars, n = 22 recordings from 11 mice) and HFruD (dark lines and bars, n = 32 recordings from 16 mice) animals. (1) Representative EOG traces after odorant stimulation (dark square) at 1:1000 dilution in mineral oil. (2) Amplitudes of EOG responses. Lines represent mean amplitudes values (±SEM) for different concentrations of odorants. *p < 0.05, **p < 0.01 and ***p < 0.001 after two-ways ANOVA followed by Fisher’s LSD post-hoc tests. (3–6) EOG kinetics at 1:1000 dilution in mineral oil. Bar graphs represent mean values (±SEM). **p < 0.01, ***p < 0.001 after Student’s t test. (3) Area under curve. (4) Rise time (time needed between 10 and 90% of the maximum response). (5) Fast decay time (between 100 and 80% of the maximum response). (6) Slow decay time (between 40 and 20% of the maximum response).
