Table 1 The individual-specific acoustic simulation results of the FUS stimulation to the V1.

From: Transcranial focused ultrasound stimulation of human primary visual cortex

ID

Gender

AI@target Isppa (W/cm2)

AImax@ROI Isppa (W/cm2)

MI@target

MImax@ROI

Deviation from the focus (mm)

Skull thickness (mm)

Subject responsiveness

h1

M

4.8

6.3

0.8

0.9

2.0

5.7

Yes

h2

F

1.2

3.7

0.4

0.7

4.0

6.8

Yes

h3

M

5.6

7.0

0.8

0.9

2.0

2.8

Yes

h4

F

2.7

4.5

0.6

0.7

2.0

5.6

Yes

h5

M

4.0

11.6

0.7

1.2

2.0

3.8

Yes

h6

M

2.3

3.2

0.5

0.6

4.0

7.8

Yes

h7

M

2.0

7.0

0.5

0.9

2.0

6.7

Yes

h8

M

1.5

1.7

0.4

0.4

2.0

6.7

Yes

h9

M

3.7

6.3

0.7

0.9

2.0

4.7

Yes

h10

M

1.3

3.2

0.4

0.6

4.0

6.7

Yes

h11

M

2.3

2.3

0.5

0.5

0.0

5.6

Yes

h12

M

5.3

5.3

0.8

0.8

0.0

2.1

Partial

h13

M

6.6

9.1

0.9

1.1

2.0

2.3

Partial

h14

F

3.2

5.1

0.6

0.8

2.0

6.6

No

h15

M

2.7

5.5

0.6

0.8

2.0

4.8

No

h16

M

3.7

3.7

0.7

0.7

0.0

6.7

No

h17

M

0.7

4.8

0.3

0.8

16.1

7.8

No

h18

F

1.2

1.7

0.4

0.4

8.2

6.9

No

h19

F

1.7

3.7

0.4

0.7

7.2

8.7

No

 

Mean

3.0

5.0

0.6

0.8

3.3

5.7

 

s.d.

1.7

2.5

0.2

0.2

3.8

1.9

  1. The estimated acoustic intensity, in terms of Isppa and the corresponding mechanical index at the intended target location (AI@target, MI@target) and the maximum values within the surroundings (AImax@ROI, MImax@ROI), along with the estimated spatial deviations in targeting during the fMRI-FUS session. See also Supplementary Fig. S1. Each subject’s skull thickness measured along the sonication path and responsiveness to the stimulation are also shown. Note that the incident acoustic intensity was 16.6 W/cm2 Isppa. M and F denote male and female, respectively.