Table 1 QTL information for body mass, total brain mass and cerebellum QTL.

From: The domesticated brain: genetics of brain mass and brain structure in an avian species

Trait

chr

pos

LOD

r-sq

add +/− s.e

dom +/− s.e.

lower CI

upper CI

selective sweeps present

body mass (212 days)

1

510

43.5

21.5

235 +/− 28

−20 +/−38

507

516

 

total brain mass

1

1516

5.3

3.3

0.06 +/− 0.02

−0.06 +/−0.04

1494

1583

119.46 LR (SPAC17A2), 127.88 LR (ARHGAP6)

total Cerebellum mass

1

1593

13.5

9.9

0.012 +/−0.005

−0.023 +/−0.007

1586

1598

127.88 LR

relative Cerebellum

1

1945

4.8

4.8

0.003 +/−0.001

0.005 +/−0.002

1931

1956

179.66 LR (UBL3), 182.6 LR (FGF9)

total Cerebellum mass

1

2204

9.3

6.6

0.0004 +/−0.004

−0.004 +/−0.005

2196

2224

MAP6, CCKBR, PLEKHB1

total Cerebellum mass

3

448

8.5

6

0.005 +/−0.005

0.022 +/−0.007

442

458

62,62 LR (KNF217), 64.04 LR (SERINC1)

total brain mass

3

448

8.7

5.6

−0.12 +/−0.07

0.25 +/−0.09

444

454

62,62 LR (KNF217), 64.04 LR (SERINC1)

body mass (212 days)

4

265

8.6

4.7

8.1 +/−9.8

19.8 +/−12.3

254

274

 

relative Cerebellum

5

124

4.8

4.8

0.002 +/−0.004

−0.03 +/−0.006

106

144

18.8 LR (FGF3), 19.4 LR (SHANK1), 20.2 LR (CAT), 20.5 LR (CD44)

body mass (212 days)

6

207

5

1.9

26 +/−8

30 +/−11

195

214

 

relative Cerebellum

7

159

7.4

7.6

0.005 +/−0.002

0.004 +/−0.002

150

171

 

total Cerebellum mass

7

174

5.9

4.1

0.019 +/−0.005

0.003 +/−0.005

150

176

23.04 AD (TANK1)

total brain mass

7

200

6.6

4.2

0.02 +/−0.018

−0.04 +/−0.03

190

212

23.04 AD (TANK1), 23.1 AD, 25.42 LR (BIN1), 25.9 LR

total brain mass

9

51.1

13.6

8.9

0.018 +/−0.017

−0.04 +/−0.02

48

60

 

body mass (212 days)

12

64

4.4

1.7

35 +/−10

20 +/−14

45

79

 

body mass (212 days)

24

14

9.5

5

0.8 +/−9.1

38 +/−11

6

18

 

body mass (212 days)

27

68

4.2

1.6

38 +/−11

−1.8 +/−9.8

56

80

 
  1. Table contains QTL locations (both the chromosome and the position in centiMorgans), % variance explained by each QTL (r-squared), additive and dominance effect sizes (positive values for additive values indicate a larger QTL effect size in domestic genotype birds, negative a larger value in wild genotype birds). The lower and upper bounds of the 95% confidence interval (C.I) are noted. The total QTL region is therefore the region bounded between these two limits. Locations of selective sweeps are also provided, with AD indicating the sweep is present in both Broiler and Layer birds, and LR indicating the sweep is specific to Layer birds. For sweeps present in cerebellum and total brain mass QTL any genes present within these sweeps are also provided after the sweep location. Cerebellum QTL are marked in bold.
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