Table 3 Binary logistic regression analysis of the association of first-trimester TBA with clinical variables and adverse pregnancy outcomes.

From: Elevated First-Trimester Total Bile Acid is Associated with the Risk of Subsequent Gestational Diabetes

 

GDM

Macrosomia

Caesarean section

PROM

Preeclampsia

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

TBA

1.31 (1.15–1.50)**

1.53 (1.13–2.08)**

1.10 (0.87–1.39)

0.96 (0.70–1.32)

0.84 (0.42–1.69)

Age

1.07 (1.03–1.12)***

1.00 (0.90–1.11)

0.96 (0.90–1.03)

1.02 (0.93–1.11)

1.21 (1.01–1.44)*

BMI

1.06 (1.01–1.10)*

1.25 (1.11–1.40)***

1.13 (1.04–1.23)**

1.08 (0.96–1.21)

1.17 (0.97–1.40)

SBP

1.02 (1.01–1.03)**

1.02 (0.98–1.05)

1.02 (1.00–1.04)

1.01 (0.99–1.04)

1.03 (0.98–1.08)

DBP

1.02 (1.01–1.04)**

0.98 (0.94–1.02)

1.00 (0.98–1.03)

1.00 (0.96–1.03)

1.10 (1.02–1.15)*

ChE

1.01 (1.00–1.01)***

1.00 (1.00–1.01)

1.00 (0.99–1.00)

1.00 (1.00–1.01)

1.02 (1.00–1.03)*

TC

0.97 (0.83–1.14)

1.17 (0.77–1.77)

0.95 (0.71–1.26)

0.83 (0.59–1.18)

1.22 (0.64–2.34)

TG

1.17 (1.01–1.35)*

1.26 (0.96–1.64)

1.08 (0.85–1.35)

1.24 (0.89–1.72)

0.98 (0.50–1.93)

UA

1.00 (1.00–1.01)

1.00 (1.00–1.01)

1.01 (1.00–1.01)

1.00 (0.99–1.00)

1.01 (1.00–1.02)

  1. GDM, gestational diabetes mellitus; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; ChE, cholinesterase; TBA,
  2. total bile acid; UA, uric acid; TC, total cholesterol; TG, total triglycerides; PROM, premature rupture of membrane. *P < 0.05, **P < 0.01, ***P < 0.001.
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