Table 2 Estimated coefficients for a generalized logistic regression (see equation 5 for definition of parameters) of the relationship between various injury phenotypes and mean strain.
From: Stretch Injury of Human Induced Pluripotent Stem Cell Derived Neurons in a 96 Well Format
Phenotype | y0 | yf | k | Et | R2 |
|---|---|---|---|---|---|
Neurite Length/Cell (μm) | 141 (134.3, 147.7) | 31.55 (23.22, 39.88) | 14.43 (8.819, 20.03) | 0.339 (0.312, 0.366) | 0.834 |
Cell Viability (% Thawed Viability) | 78.44 (75.28, 81.59) | 18.91 (14.66, 23.16) | 18.43 (10.88, 25.98) | 0.357 (0.335, 0.380) | 0.828 |
Processes/Cell | 3.36 (3.247, 3.473) | 1.327 (1.175, 1.48) | 16.43 (9.841, 23.01) | 0.353 (0.329, 0.378) | 0.828 |
Total Neurite Length (μm) | 43411 (40824, 45998) | 2645 (−237.6, 5527) | 16.46 (9.47, 23.46) | 0.322 (0.296, 0.349) | 0.819 |
Branches/Cell | 2.462 (2.281, 2.643) | 0.199 (−0.018, 0.417) | 15 (7.265, 22.73) | 0.334 (0.3, 0.369) | 0.745 |
Total Processes | 1063 (985.8, 1141) | 103.3 (8.95, 197.7) | 17.24 (7.172, 27.32) | 0.337 (0.303, 0.37) | 0.708 |
Viable Cells/Image | 312.8 (294.3, 331.2) | 77.03 (51.43, 102.6) | 17.8 (7.213, 28.38) | 0.361 (0.328, 0.395) | 0.689 |
Total Branches | 801.5 (705, 898.1) | 15.94 (−79.97, 111.8) | 15.8 (4.113, 27.49) | 0.305 (0.255, 0.355) | 0.589 |
Dead Cells/Image | 271.1 (239.9, 302.3) | 528.2 (489.6, 566.9) | 24.58 (−1.24, 50.4) | 0.356 (0.313, 0.4) | 0.459 |
