Table 1 Clinicopathologic features in patients with rectal cancer according to TTDpR.

From: Time to lowest postoperative carcinoembryonic antigen level is predictive on survival outcome in rectal cancer

Characteristic

Overall population (N = 155)

TTDpR

>4.5 weeks (N = 75)

</ = 4.5 weeks (N = 80)

p-value

Age-yr, median (range)

55 (21–78)

56 (21–75)

54 (25–78)

0.242

BMI, median (range)

22.05 (14.22–33.79)

21.80 (15.63–33.79)

22.39 (14.22–30.86)

0.457

Sex, no.(%)

   

0.416

 Male

92 (59)

47 (63)

45 (56)

 

 Female

63 (41)

28 (37)

35 (44)

 

Smoking history, no.(%)

   

0.548

 No

121 (78)

57 (80)

64 (78)

 

 Yes

34 (22)

18 (20)

16 (22)

 

Tumor category, no.(%)

   

0.849

 T1

4 (3)

2 (3)

2 (2)

 

 T2

25 (16)

12 (16)

13 (16)

 

 T3

113 (73)

55 (73)

58 (73)

 

 T4

13 (8)

6 (8)

7 (9)

 

Nodal category, no.(%)

   

0.206

 N0

61 (39)

33 (44)

28 (35)

 

 N1-2

94 (61)

42 (56)

52 (65)

 

TNM Stage, AJCC, no.(%)

   

0.512

 I

19 (12)

10 (13)

9 (11)

 

 II

42 (27)

23 (31)

19 (24)

 

 III

94 (61)

42 (56)

52 (65)

 

Differentiation degrade, no.(%)

   

0.450

 Low

40 (26)

20 (27)

20 (25)

 

 Moderate

76 (50)

39 (54)

37 (47)

 

 High

36 (24)

14 (19)

22 (28)

 

Lymphovascular invasion, no.(%)

   

0.310

 Positive

21 (13)

67 (89)

67 (84)

 

 Negative

134 (87)

8 (11)

13 (16)

 

Neural invasion, no.(%)

   

0.298

 Positive

26 (17)

15 (20)

11 (14)

 

 Negative

129 (83)

60 (80)

69 (86)

 

Preoperative CEA

   

0.038

 Normal

115 (74)

50 (67)

65 (81)

 

 Elevated

40 (26)

25 (33)

15 (19)

 

Distance from anal verge, no. (%)

   

0.474

 <5 cm

58 (38)

30 (41)

28 (35)

 

 5–12 cm

94 (62)

43 (59)

51 (65)

 

 Unknown

3

0

3

 

Surgical approach, no.(%)

   

0.245

 Low anterior resection

114 (73)

51 (68)

63 (79)

 

 Abdminoperineal resection

15 (10)

10 (13)

5 (6)

 

 Parks procedure

26 (17)

14 (19)

12 (15)

 

Neoadjuvant treatment, no.(%)

   

0.507

 No

107 (69)

52 (71)

53 (66)

 

 Yes

48 (31)

21 (29)

27 (34)