Table 3 Multivariate analysis of risk factors for three-year DFS.

From: Time to lowest postoperative carcinoembryonic antigen level is predictive on survival outcome in rectal cancer

Risk Factor

HR (95% CI)

p-value

Disease-free survival

 AJCC Stage III

3.94 (1.41–11.06)

0.009

 Perineural invasion

3.95 (1.69–9.26)

0.002

 TTDpR

1.12 (1.03–1.21)

0.006

Overall survival

 AJCC Stage III

8.50 (1.14–63.29)

0.037

 Distance from anal verge <5 cm

2.62 (1.30–5.30)

0.007

 TTDpR

1.17 (1.06–1.28)

0.001