Figure 1: Generation of iPSCs from two healthy volunteers and a patient with LQTS3 and BrS.
From: Embryonic type Na+ channel β-subunit, SCN3B masks the disease phenotype of Brugada syndrome
(A) Electrocardiogram from the patient during sinus rhythm. QTc 520 ms. (B) Sequence analysis of genomic SCN5A in the patient. (C) Immunofluorescence staining for stem cell markers (OCT4, NANOG, SSEA3, SSEA4, Tra1-60 and Tra1-81) in two control and two LQTS3/BrS iPSC colonies.
