Figure 5 | Scientific Reports

Figure 5

From: Mst1 inhibits CMECs autophagy and participates in the development of diabetic coronary microvascular dysfunction

Figure 5

Mst1/sirt1 signaling is involved in the development of coronary microvascular damage in diabetes.

(A) Cardiac microvessel integrity evaluated by scanning electron microscopy (n = 5); (B–D) Echocardiographic evaluation of LVEF and LVFS (n = 5) (Magnification: upper panel x10,000; lower panel x5,000); (E,F) LVESD and LVEDD measurements. *P < 0.05 vs non-DM; #P < 0.05 vs DM. (G,H) Representative images of TUNEL staining and quantitative analyses of apoptotic CMECs. The columns and error bars represent means and SE. *P < 0.05 vs Con; #P < 0.05 vs HG.

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