Table 2 Subgroup analysis according to the type of arrest (OHCA vs. IHCA).

From: Efficacy of extracorporeal cardiopulmonary resuscitation compared to conventional cardiopulmonary resuscitation for adult cardiac arrest patients: a systematic review and meta-analysis

 

Survival

Neurologic outcomes

Characteristics

N

OR (95% CI)

p value for heterogeneity

I2, %

N

OR (95% CI)

p value for heterogeneity

I2, %

OHCA

All

3

2.26 (0.45–11.20)

<0.00001

93

3

3.14 (0.66–14.85)

0.007

80

Study type

 ROS

1

0.63 (0.39–1.03)

N/A

1

0.94 (0.41–2.14)

N/A

 POS

2

4.89 (2.75–8.70)

<0.00001

0

2

7.12 (2.68–18.95)

0.52

0

Assessment of quality

 High*

2

1.43 (0.23–9.00)

0.02

83

2

1.72 (0.38–7.71)

0.10

63

 Low

1

5.03 (2.69–9.41)

N/A

1

8.94 (2.69–29.64)

N/A

IHCA

All

4

2.40 (1.44–3.98)

0.63

0

3

2.63 (1.38–5.02)

0.36

3

Study type

 ROS

3

2.44 (1.35–4.41)

0.43

0

2

2.95 (0.19–9.59)

0.16

51

 POS

1

2.30 (0.86–6.13)

N/A

1

2.44 (0.88–6.76)

N/A

Assessment of quality

 High*

3

2.52 (1.44–4.43)

0.46

0

3

2.63 (1.38–5.02)

0.36

3

 Low

1

1.93 (0.60–6.23)

N/A

—

—

—

  1. Abbreviations: N, the number of studies; OR, odds ratio; 95% CI, 95% confident interval; OHCA, out-of-hospital cardiac arrest; IHCA, in-hospital cardiac arrest; ROS, retrospective observational study; POS, prospective observational study; N/A, not available.
  2. *High-quality studies were those that achieved >9 points in quality assessment. The propensity score matching method was used in all high-quality studies.
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