Figure 3: Deletion one PRL1 allele in PRL2−/− results in male infertility due to no sperm production.
From: Role of phosphatase of regenerating liver 1 (PRL1) in spermatogenesis
(A) Sexual desire was measured by plug rate. (B,C) Reproductive performance was measured by pregnancy rate (B) and little size (C). (D) The sperm number was determined by calculating the sperms from epididymis. (E) Caudal epididymis sections from 3 months old male mice were histologically examined by H&E staining. Scale bar = 50 μm. (F) Electron microscopic analysis of epididymal sperm from the indicated genotypes. The typical “9 + 2” microtubule structure indicates the transverse section of the sperm. Scale bar = 500 nm. *p < 0.05, **p < 0.01, ***p < 0.001 (Student’s t test). Data are representative of at least three independent experiments (mean and SD).
