Table 2 Distribution of offspring by double heterozygous-double heterozygous (PRL1+/−/PRL2+/−) mating at weaning indicates embryonic lethality of PRL1−/−/PRL2−/− double knockout mice and a survival disadvantage of PRL1−/−/PRL2+/− and PRL1+/−/PRL2−/− mice.
From: Role of phosphatase of regenerating liver 1 (PRL1) in spermatogenesis
PRL1 | +/+ | +/− | −/− | n | χ2 | p | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
PRL2 | +/+ | +/− | −/− | +/+ | +/− | −/− | +/+ | +/− | −/− | |||
Observed | 22 | 56 | 30 | 54 | 110 | 27 | 18 | 35 | 0 | 352 | 45.10 | <0.001 |
Expected | 22 | 44 | 22 | 44 | 88 | 44 | 22 | 44 | 22 | |||
