Table 1 The effect of aguamiel concentrate or its extracted saponins consumption for 12 weeks on the biochemical parameters in mice.

From: Aguamiel concentrate from Agave salmiana and its extracted saponins attenuated obesity and hepatic steatosis and increased Akkermansia muciniphila in C57BL6 mice

Parameter

C

HF

HFAC

HFL

HFH

Total cholesterol (mg/dL)

120.9 ± 30.6

146.4 ± 41.6

122.4 ± 29.4

118.4 ± 33.3

118.0 ± 9.5

LDL-cholesterol (mg/dL)

22.4 ± 10.6*

37.5 ± 18.8

23.6 ± 8.9*

21.2 ± 8.6*

20.8 ± 2.4**

HDL-cholesterol (mg/dL)

119.4 ± 27.2

141.3 ± 32.7

122.8 ± 26.2

119.1 ± 31.2

123.1 ± 7.9

Triacylglycerides (mg/dL)

100.9 ± 16.2

90.0 ± 21.5

90.8 ± 25.4

92.7 ± 22.11

74.8 ± 33.0

Glucose (mg/dL)

255.4 ± 43.7

282.3 ± 38.7

284.0 ± 45.0

279.7 ± 53.6

256.9 ± 32.5

Insulin (ng/dL)

1.29 ± 0.3**

1.44 ± 0.5

1.11 ± 0.1***

1.17 ± 0.2***

1.00 ± 0.0***

HOMA-IR

20.2 ± 5.6

25.1 ± 13.2

19.14 ± 4.0

19.7 ± 6.0

15.3 ± 2.0*

  1. Data are presented as mean ± STD DEV (n = 7). Statistical analysis was done with one-way ANOVA followed by Dunnett’s post hoc test compared to the HF group. Significance *P < 0.05, **P < 0.01, ***P < 0.001. C: control; HF: High-fat; HFAC: High-fat with aguamiel concentrate; HFL: High-fat with low saponin dose; HFH: High-fat with high saponin dose.
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