Table 2 Inhibitory effects on fMLF/CB-activated neutrophils of isolates and synthetics.

From: Ilex kaushue and Its Bioactive Component 3,5-Dicaffeoylquinic Acid Protected Mice from Lipopolysaccharide-Induced Acute Lung Injury

Compounds

IC50 (μM)

Compounds

IC50 (μM)

O2.− generation

HNE

O2.− generation

HNE

1

1.54 ± 0.29

>10

9

0.99 ± 0.26

1.07 ± 0.33

2

2.81 ± 1.00

>10

10

>10

>10

3

2.56 ± 1.06

>10

11

>10

>10

4

1.70 ± 0.28

>10

12

>10

>10

6

1.92 ± 0.54

>10

13

>10

>10

7

1.49 ± 0.38

>10

14

>10

>10

QA

>10

>10

15

>10

7.99 ± 1.18

CA

1.42 ± 0.02

>10

17

>10

>10

RA

1.29 ± 0.09

>10

18

>10

>10

THBA

1.14 ± 0.08

>10

19

>10

>10

p-CA

>10

>10

11-1

>10

>10

3-HCA

>10

>10

11-2

>10

>10

FA

>10

>10

14-1

4.77 ± 0.40

2.84 ± 1.02

 

—

—

15-1

0.14 ± 0.09

0.06 ± 0.01

 

—

—

15-2

0.26 ± 0.10

0.20 ± 0.02

  1. QA, quinic acid; CA, caffeic acid; RA, rosaminiric acid; THBA, 3,4,5-trihyroxybenzoic acid; p-CA, p-coumaric acid; 3-HCA, 3-hydroxycinnamic acid; FA, ferulic acid. Data were presented as mean ± S.E.M. (n ≥ 3).
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