Figure 1
Discriminatory capacity of ELISA and UCP-LFA.
To compare the ability of ELISA (dotted line) and UCP-LFA (solid line) to discriminate between individuals with or without disease ROC curves were computed using data of MB patients and EC. Areas under the curve (AUCs) were compared for all 10 conditions tested, shown in the lower right corner of each graph. (a) ROC curves for IP-10 stimulated and unstimulated samples based on concentration in pg/ml, showing an improved AUC for the UCP-LFA for IP-10Nil and IP-10WCS. (b) ROC curves for IL-10 stimulated and unstimulated samples based on concentration in pg/ml, showing an improved (IL-10Nil) or equal AUC for UCP-LFA. (c) ROC curves for CCL4 stimulated and unstimulated samples based on concentration in pg/ml, showing comparable values for UCP-LFA and ELISA. (d) ROC curves for anti-PGL-I IgM in unstimulated samples based on ratio, showing comparable AUCs for ELISA and UCP-LFA.
