Figure 1 | Scientific Reports

Figure 1

From: Losartan reduces ensuing chronic kidney disease and mortality after acute kidney injury

Figure 1

AKI induced by nephrectomy followed by contralateral renal ischemia-reperfusion injury leading to development of ensuing CKD.

(a,b) Blood urea nitrogen (BUN) and creatinine plasma levels, (c) urine albumin-creatinine ratio (ACR) and (d) systolic blood pressure (BP) in adult male mice 3 months after sham operation, nephrectomy (NX) and NX followed by 26- or 28-minute ischemia/reperfusion to contralateral kidney (NX+IRI-26 min, NX+IRI-28 min) respectively. N = 10, 20, 18 and 16 for sham, NX, NX+IRI-26 min and NX+IRI-28 min respectively. *P < 0.05, ‡P < 0.001.

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