Figure 4
From: Losartan reduces ensuing chronic kidney disease and mortality after acute kidney injury
CKD development after AKI in a larger mouse cohort.
(a,b) Time course systolic BP and urine ACR after NX or NX+IRI. (c) Plasma levels of BUN and creatinine at 5 months after surgery. (d) Representative images of Masson’s trichrome stain in kidneys at 5 months after surgery. (e) Quantification of interstitial fibrosis area in Masson’s trichrome stain of kidneys. (f) Representative images of PAS stain of kidneys showing shrunken glomerular tuft with widened Bowman’s space at 5 months after surgery. Scale bar, 100 μm. †P < 0.01, ‡P < 0.001. N was shown in (a,b).
