Figure 6
From: Losartan reduces ensuing chronic kidney disease and mortality after acute kidney injury
Losartan attenuates fibrosis in ensuing CKD after AKI.
(a,b) Representative images and quantification of interstitial fibrosis area in kidneys by Masson’s trichrome stain at 5 months after surgery and specific treatment when N = 32 (NX), 27 (NX+IRI), 37 (Losartan) and 33 (Hydralazine) as shown in Fig. 5e. (c,d) Renal glomerular volume, glomerulosclerosis and the percentage of glomeruli with shrunken tufts and widened Bowman’s space. *P < 0.05, ‡P < 0.001.
