Figure 5
From: GPR30 regulates diet-induced adiposity in female mice and adipogenesis in vitro
GPR30 deficiency increased body temperature but had no significant effect on energy expenditure and fatty acid oxidation.
Female WT or KO mice were fed a STD or HFD for 23 wks. Rectal body temperatures were measured at 12, 19 and 22nd wk (A). The average energy expenditure (B) and cage activity during light time and dark time (C) were measured after 23 wks of treatment. Fatty acid oxidation in white adipose tissues (D) and skeletal muscle (E) from WT and KO female mice were also determined. Data are mean ± SEM (n = 8 mice/group). *p < 0.05.
