Figure 2: Maternal high-fat diet feeding during lactation reprograms body composition and metabolic syndrome in adult offspring. | Scientific Reports

Figure 2: Maternal high-fat diet feeding during lactation reprograms body composition and metabolic syndrome in adult offspring.

From: Maternal high-fat diet during lactation impairs thermogenic function of brown adipose tissue in offspring mice

Figure 2

(a) Body weight of offspring from control (Con) and high-fat diet (HFD) feeding dams (n = 8 per group). (b,c) Fat tissue weight (BAT: brown adipose tissue; iWAT: inguinal adipose tissue; eWAT: epididymal adipose tissue; Mes: mesenteric fat) (b) and ratio of fat tissue to body weight (c) in adult offspring at 16-week of age (n = 8 Con and n = 6 HFD); (d) Representative images of eWAT and iWAT sections stained with H&E. (e,f) Glucose tolerance test (GTT; at 14-week of age) (e) and insulin tolerance test (ITT; at 15-week of age)) (f) of adult offspring (n = 5 per group). AUC: area under curve. Data are presented as Means ± S.E.M. *P < 0.05; **P < 0.01; ***P < 0.001 as determined using a Student’s t-test.

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