Table 4 Inhibitory Activities of Tea Polyphenols on Pancreatic Lipase.
From: Prediction and evaluation of the lipase inhibitory activities of tea polyphenols with 3D-QSAR models
No | Compoud Name | IC50(μM) | pIC50 |
|---|---|---|---|
1 | assamicain A | 0.13 | 6.8861 |
2 | assamicain B | 0.21 | 6.6778 |
3 | (−)-epicatechin (EC) | >30 | 4.5229 |
4 | (−)-epicatechin-3-O-gallate (ECG) | 0.34 | 6.4685 |
5 | (−)-epigallocatechin (EGC) | >30 | 4.5229 |
6 | (−)-gallocatechin-3-O-gallate (GCG) | 0.57 | 6.2441 |
7 | (−)-epigallocatechin-3-O-gallate (EGCG) | 0.39 | 6.4089 |
8 | (−)-epigallocatechin-3,5-di-O-gallate | 0.11 | 6.9586 |
9 | (−)-epicatechin 3-O-(3′-O-methyl)-gallat | 0.74 | 6.1308 |
10 | (−)-epigallocatechin-3-O-p-coumaroate | 0.97 | 6.0132 |
11 | (−)-epicatechin(4β-8)-(−)-epigallocatechin 3-O-gallate | 0.16 | 6.7959 |
12 | (−)-epigallocatechin (4β-8)-(−)-epicatechin-3-O-gallate | 1.23 | 5.9101 |
13 | (−)-epicatechin-3-O-gallate-(4β-8)-(−)-epigallocatechin3-O-gallate | 0.93 | 6.0315 |
14 | (−)-epigallocatechin-3-O-gallate-(4β-8)-(−)-epicatechin 3-O-gallate | 0.69 | 6.1612 |
15 | (−)-epiafzelechin 3-O-gallate | 2.81 | 5.5513 |
16 | (+)-catechin (4α-8) (−)-epigallocatechin | 8.7 | 5.0605 |
17 | (+)-catechin (4α-8) (−)-epigallocatechin 3-O-gallate | 0.19 | 6.7212 |
18 | (+)-gallocatechin (4α-8) (−)-epicatechin | 3.28 | 5.4841 |
19 | Oolongtheanin | 0.25 | 6.6021 |
20 | oolonghomobisflavan A | 0.11 | 6.9586 |
21 | mono-desgalloyl oolonghomobisflavan A | 0.3 | 6.5229 |
22 | di-desgalloyl oolonghomobisflavan B | 2.29 | 5.6402 |
23 | procyanidin B2 | 8.75 | 5.0580 |
24 | procyanidin B3 | 3.28 | 5.4841 |
25 | procyanidin B4 | 17.29 | 4.7622 |
26 | prodelphinidin A2-3′-O-gallate | 0.18 | 6.7447 |
27 | prodelphinidin B2 | 3.24 | 5.4895 |
28 | prodelphinidin B2- 3′-O-gallate | 2.16 | 5.6655 |
29 | prodelphinidin B2-3,3′-di-O-gallate | 0.1 | 7.0000 |
30 | prodelphinidin B4 | 6.85 | 5.1643 |
31 | prodelphinidin B4-3-O-gallate | 0.25 | 6.6021 |
32 | prodelphinidin B5-3,3′-di-O-gallate | 0.61 | 6.2147 |
33 | theaflavin-3′-O-gallate | 0.13 | 6.8861 |
34 | theaflavin-3,3′-di-O-gallate | 0.1 | 7.0000 |
35 | theasinensin A | 0.15 | 6.8239 |
36 | theasinensin B | 0.3 | 6.5229 |
37 | theasinensin C | 16.38 | 4.7857 |
