Figure 7
Enzyme kinetic plots (A,C,E,G), V/[S]-V plots (B,F′) and Eadie-Hofstee plots (B″,D,F″,H) of M1 (quercetin-7-glucuronide) formation by UGT1A9*NCFP/2B7*NHA co-expression systems. Glucuronidation rates are mean ± SD of three independent determinations and normalized according to relative expression levels. The respective kinetic constants are presented in Table 4.
