Figure 8

Schematic diagram showing the regulation of HA in HBx-induced proliferation and autophagy.
HA inhibits HBx, HBV DNA and HBsAg levels. Further, HA inhibits HBx-induced cell proliferation via c-myc/akt/β-catenin pathway and autophagosome formation via SIRT-1/beclin1 pathway in Hep G2.2.1.5 cells.