Figure 1: Expression profiling of microRNAs in locally invasive breast tumors and normal tissues.
From: Dual targeting of ANGPT1 and TGFBR2 genes by miR-204 controls angiogenesis in breast cancer
(A) Unsupervised hierarchical clustering analysis displaying the differential expression of microRNAs in breast tumors relative to normal tissues from TLDA. The heat map (Spearman correlation, Euclidean distance) represents a cluster analysis of the logarithm of transformed ΔΔCt values of the differentially expressed microRNAs. Color key: upregulated microRNAs (red); downregulated microRNAs (green). Blue upper bar, normal tissues; red upper bar, tumor tissues. (B) Validation of expression levels of eight microRNAs using Taqman qRT-PCR assay (grey) in comparison with data obtained from TLDA (white). Data were expressed as mean ± S.D.
