Figure 2 | Scientific Reports

Figure 2

From: Analysis of microRNA and Gene Expression Profiles in Multiple Sclerosis: Integrating Interaction Data to Uncover Regulatory Mechanisms

Figure 2

The miRNA-based network dysregulated in multiple sclerosis.

This is a circular view of the microRNA (miRNA)-based network. Green edges are activating edges, red ones are inhibiting edges. Yellow nodes represent miRNAs, blue nodes represent transcription factors (TFs) and white ones represent molecules that are not miRNAs or TFs. The size of the nodes is proportional to the degree of the nodes, i.e., the number of incoming and outgoing edges. The three biggest TF nodes are SP4, SP3 and SP1 and the biggest miRNA nodes correspond to miR-125a-5p and miR-221-3p.

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