Figure 5 | Scientific Reports

Figure 5

From: TM4 of the glutamate transporter GLT-1 experiences substrate-induced motion during the transport cycle

Figure 5

Inhibition of transport of cysteine mutants by cadmium.

HeLa cells expressing I93C/V241C (A) or I97C/V241C (B) or the indicated controls were washed once with choline chloride-containing solution and assayed for transport in the presence or absence of 500 μM cadmium chloride. Values shown are the percentage of the activity in the presence relative to the absence of 500 μM cadmium chloride. Values represent the means ± S.E. of at least three different experiments done in triplicates. Values that are significantly different from that of CL-GLT-1 were determined by one-way ANOVA (*P < 0.05; **P < 0.01).

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