Table 1 Regression analysis and factors associated with mother-to-child transmission of HIV.
Multivariate regression Indicators | Proportion (%) | Children HIV status | Univariate regression | Multivariate regression | ||
|---|---|---|---|---|---|---|
HIV+ | HIV− | MTCT rate (%) | OR (95% CI) | OR (95% CI) | ||
Demographic Characteristics | ||||||
Age | ||||||
<25 | 316 (28.6) | 13 | 303 | 4.11 | 0.80 (0.31, 2.06) | |
25~ | 408 (36.9) | 21 | 387 | 5.15 | 1.02 (0.42, 2.44) | |
30~ | 243 (22.0) | 13 | 230 | 5.35 | 1.06 (0.41, 2.72) | |
35~ (ref) | 138 (12.5) | 7 | 131 | 5.07 | ||
Ethnic group | ||||||
Han | 493 (46.6) | 19 | 474 | 3.85 | 0.72 (0.40, 1.29) | |
Minority (ref) | 566 (53.4) | 30 | 536 | 5.30 | ||
Education | ||||||
Junior high and below (ref) | 924 (87.3) | 42 | 882 | 4.55 | ||
Senior high and above | 135 (12.7) | 7 | 128 | 5.19 | 1.15 (0.51, 2.61) | |
Marriage | ||||||
First | 759 (72.2) | 33 | 726 | 4.35 | 0.61 (0.14, 2.69) | |
Second | 264 (25.1) | 14 | 250 | 5.30 | 0.76 (0.16, 3.51) | |
Others (ref) | 29 (2.7) | 2 | 27 | 6.90 | ||
Residence registration | ||||||
Rural (ref) | 812 (76.7) | 32 | 780 | 3.94 | ||
Urban | 247 (23.3) | 17 | 230 | 6.88 | 1.80 (0.98, 3.30) | |
Monthly income | ||||||
<500 RMB (ref) | 573 (61.2) | 25 | 548 | 4.36 | ||
500–1000 RMB | 246 (26.3) | 17 | 229 | 6.91 | 1.63 (0.86, 3.07) | |
>1000 RMB | 117 (12.5) | 3 | 114 | 2.56 | 0.58 (0.17, 1.94) | |
HIV biomarkers and ARV use | ||||||
CD4 | ||||||
>=350 | 264 (71.2) | 5 | 259 | 1.89 | 2.61(1.17, 18.12) | |
200–349 | 92 (24.8) | 0 | 92 | 0 | 1.04 (0.33, 7.19) | |
<200 (ref) | 15 (4.0) | 1 | 14 | 0.93 | ||
Virusal load | ||||||
<50 | 57 (29.5) | 0 | 57 | 0.00 | ||
50–1000 | 27 (14.0) | 0 | 27 | 0.00 | ||
>1000 (ref) | 109 (56.5) | 0 | 109 | 0.00 | ||
ARV use in HIV+ mothers | ||||||
Single regimen | 413 (37.4) | 25 | 388 | 6.05 | 0.51 (0.28, 0.94) | 0.50 (0.25, 0.99) |
Multi-regimen | 505 (45.7) | 8 | 497 | 1.58 | 0.13 (0.06, 0.29) | 0.11 (0.04, 0.29)* |
No use (ref) | 187 (16.92) | 21 | 166 | 11.23 | ||
ARV use in HIV exposed children | ||||||
Yes | 1006 (93.8) | 45 | 961 | 4.47 | 0.47 (0.19, 1.14) | |
No (ref) | 66 (6.2) | 6 | 60 | 9.09 | ||
Delivery and feeding | ||||||
Delivery method | ||||||
Vaginal delivery | 645 (61.3) | 26 | 619 | 4.03 | 0.55 (0.28, 1.09) | 0.46 (0.23, 0.96)* |
Elective caesarean section | 225 (1.4) | 11 | 214 | 4.89 | 0.67 (0.29, 1.54) | 0.74 (0.37, 2.03) |
Emergency caesarean section (ref) | 183 (174) | 13 | 170 | 7.10 | ||
Feeding mode | ||||||
Formula feeding | 1033 (98.6) | 49 | 984 | 4.74 | 0.20 (0.05, 0.73) | |
Mixed feeding (ref) | 15 (1.4) | 3 | 12 | 20.00 | ||
