Table 1 Associations and Influence of A/B/O, Lewis, and secretor blood types among children with the risk of rotavirus infection.

From: P[8] and P[4] Rotavirus Infection Associated with Secretor Phenotypes Among Children in South China

Status

No. (%) of RV positive

No. (%) of RV/NoV negative

OR (95% CI), P value

No. (%) of health control

OR (95% CI), P value

Blood type

n = 75

n = 151

N=226, ^P = 0.384

n = 159

N = 234, ^P = 0.672

A

22 (29.3)

47 (31.1)

0.919 (0.502–1.682), 0.878

35 (22.0)

1.471 (0.789–2.741), 0.254

B

17 (22.7)

44 (29.1)

0.713 (0.374–1.358), 0.324

39 (24.5)

0.902 (0.471–1.728), 0.870

O

33 (44.0)

50 (33.1)

1.587 (0.899–2.801), 0.143

79 (49.7)

0.796 (0.458–1.382), 0.484

AB

3 (4.0)

10 (6.6)

0.588 (0.157–2.202), 0.552

6 (3.8)

1.063 (0.258–4.369), 1.000

Lewis status

n = 75

n = 151

N = 226, ^P = 0.004**

n = 159

N=234, ^P=0.000**

Leb+/Ley+

63 (84.0)

132 (87.4)

1.198 (0.673–1.21), 0.539

134 (84.3)

0.979 (0.462–2.075), 1.000

Lea+/Lex+

0 (0.0)

10 (5.6)

0.653 (0.592–0.719), 0.033*

20 (12.6)

0.874 (0.824–0.927), 0.001 **

Lea+b+/Lex+y+

12 (16.0)

9 (6.0)

3.005 (1.205–7.494), 0.026*

5 (3.1)

5.869 (1.985–17.339), 0.001 **

Secretor status§

n = 75

n = 151

N=226, ^P=0.033*

n = 159

N=234, ^P=0.001**

Secretor

75 (100)

141 (93.4)

1.531 (1.39–1.69), 0.033*

139 (87.4)

1.144 (1.079–1.214), 0.001 **

Nonsecretor

0 (0)

10 (6.6)

0.653 (0.592–0.719) , 0.033*

20 (12.6)

0.874 (0.824–0.927), 0.001 **

  1. NoV samples were excluded from patients without RV infection; Unadjusted odds ratios (OR) and 95% confidence intervals (CIs); §Leb+/Ley+ and Lea+b+/Lex+y+ were grouped into secretor and Lea+/Lex+ were grouped into nonsecretor; ^P: significance test of proportion of different HBGA phenotype between RV positive group and control group; *P < 0.05; **P < 0.01.