Figure 2 | Scientific Reports

Figure 2

From: Detection of aqueous VEGF concentrations before and after intravitreal injection of anti-VEGF antibody using low-volume sampling paper-based ELISA

Figure 2

Schematic illustration of paper-based ELISA for VEGF detection.

In the clinical setting, patients receive standard-of-care procedures: slit lamp, SD-OCT, and FAG (left panel). Paper-based ELISA requires 1 μL of aqueous humor before operation, and quantification of VEGF concentrations requires 40 μL (right panel). Further colorimetric results can be obtained using a scanner or smartphone. Ophthalmologists can determine treatment according to VEGF concentrations and SD-OCT results.

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